MSI Results

MSI testing results are usually described in one of three ways:

Microsatellite stable (MSS) – no instability is detected in any of the analyzed markers

MSI-low (MSI-L) – instability is detected in 1 of the analyzed markers

MSI-high (MSI-H) – instability is detected in 2 or more of the markers

Individuals with Lynch syndrome are most likely to have MSI-H tumors, although mutations in MSH6 sometimes result in MSI-L or MSS tumors.


Interpreting Results:

NSGC Practice Guidelines

NCCN guidelines (In GeneReviews)

Pathology Reports:

Microsatellite stable and MSI-low

Results Letters:

Physician notification letter (order request): St. Vincent Hospital